Lysis of Erythrocytes by Trichomonas Vaginal&
نویسنده
چکیده
The in vitro hemolytic activity of 4 isolates of Trichomonas vaginal& was investigated. Repetitive hemolysis assays of any one isolate showed cyclical fluctuations in hemolytic activity, varying over 24 hr of continuous culture. Maximal hemolytic activity was detected using trichomonads in the lag phase of the growth cycle. Investigations showed that hemolysis was a contact-dependent phenomenon and microscopic investigation of samples showed a significant correlation between hemolysis and attachment of erythrocytes to the trichomonad surface. Quantitative data from cytoadherence assays using [5~Cr]-labeled erythrocytes were consistent with these observations. It is suggested that hemolytic activity is dependent upon adherence of red blood cells to the surface of T. vaginalis.
منابع مشابه
Identification and Evaluation of Trichomonas vaginalis in Wesley Guild Hospital Ilesha, Nigeria
The Identification and evaluation of Trichomonas vaginalis among women was performed over a period of three months in Ilesha. The aim of this study was to determine the prevalence of Trichomonas vaginalis in women in relation to different samples collected and level of education. 310 samples from high vaginal, endocervical and urethral regions of female patients were analyzed using Gram stainin...
متن کاملPrevalence of trichomonas vaginalis in women referred to vali- asr polyclinic and the health center number 3 in Sirjan city
To determine the prevalence of trichomoniasis in Sirjan city, the vaginal discharges of 500 women were examined by direct smear and culture methods from June to December 1992. ( Two hundred thirty women referred to vali-asr polyclinic and 270 to the health center number 3). The mean age of the women was 30 years and a higher percentage of referrals were between 30-34 years. In respect to the...
متن کاملRole of pH on Adhesion of Trichomonas Vaginalis Isolated from Symptomatic & Asymptomatic Women to Vaginal Epithelial Cells in Vitro
Background: Vaginal epithelium is the most important site for initial contact of the parasite infection in humans. Objective: To investigate the effect of Lactobacillus acidophilus (LA) and pH on attachment of T. vaginalis isolated from symptomatic and asymptomatic patients to vaginal epithelial cells (VECs). Methods: Following 1-4 hrs contact of parasite with VECs, wet mounts were prepared and...
متن کاملHemolytic activity of Trichomonas vaginalis and Tritrichomonas foetus.
The hemolytic activity of live isolates and clones of Trichomonas vaginalis and Tritrichomonas foetus was investigated. The isolates were tested against human erythrocytes. No hemolytic activity was detected by the isolates of T. foetus. Whereas the isolates of T. vaginalis lysed erythrocytes from all human blood groups. No hemolysin released by the parasites could be detected. Our preliminary ...
متن کاملComparison of direct microscopic examination and culture methods sensitivity for diagnosis of Trichomonas vaginalis in Tabriz health care centers visitors
Background: Trichomonas vaginalis is a common pathogen with worldwide distribution. It is estimated that worldwide 180 million people are infected annually. Trichomoniasis is associated with vaginitis, cervicitis, low birth weight, and preterm delivery in pregnant women in addition, it is a cofactor in HIV transmission. Diagnosis of disease is traditionally depends on the microscopic observatio...
متن کامل